Peptide Mechanism Maps
Each map summarises a major pathway that peptides discussed on this site interact with — receptor targets, downstream signalling, related peptides, related research stacks, and evidence caveats.
GH axis (GHRH / GHRP / IGF-1)
Hypothalamic-pituitary-GH signalling, downstream IGF-1, and the peptides that act on this axis.
Angiogenesis & VEGF / VEGFR2
How VEGF-mediated angiogenesis underlies tissue-repair claims for BPC-157 and TB-500.
NF-κB inflammation
The master inflammatory transcription factor, and the peptides claimed to modulate it.
AMPK & mitochondria
Energy-sensing kinase signalling and the mitochondrial peptides claimed to act there.
Melanocortin receptors (MC1R–MC5R)
Pigmentation, libido and energy homeostasis pathways acted on by melanocortin peptides.
Thymic / immune signalling
Thymalin, thymosin α-1 and related thymic-derived peptide claims.
Wound healing phases
Hemostasis → inflammation → proliferation → remodelling, and where peptides are claimed to act.
GLP-1 / GIP / glucagon receptors
Incretin receptor pharmacology, dual / triple agonist concepts, and regulatory sensitivity.
Mitochondrial-derived peptides (MDPs)
MOTS-c, humanin and the SHLPs — peptides encoded within mitochondrial DNA that circulate as hormones.
Pages on PeptideStacks are reviewed when relevant new evidence becomes available. If you spot an error or have new evidence to suggest, please use our corrections policy.